Clinical application of Bionect (Hyaluronic Acid Sodium Salt) in wound care by cesarean section and episiotomy
Ivanov, C.; Michova, M.; Russeva, R.; Batashki, I.
Akusherstvo i Ginekologiia 46 Suppl. 4: 20-26
2007
ISSN/ISBN: 0324-0959 PMID: 19708195 Document Number: 11451
Hyaluronic acid is an important component of extracellular matrix and plays crucial role in wound healing by stimulation of neutrophil migration, fibroblasts proliferation and neoangiogenesis. To study the efficacy of topical application of of Bionect (Hialuronic Acid Sodium Salt) in wound care in cases of episiotomy and cesarean section surgical wounds. 27 patients, delivered by cesarean section and 20 patients with vaginal delivery with episiotomy were included in a prospective study. In 15 cases from cesarean section group and 10 cases from episiotomy group daily application of Bionect was performed. Standard wound care was applied in 12 cesarean section wounds and 10 episeotomies. All patients were monitored for wound healing disturbances on daily basis. The incidence of edema, infiltration, exudation and superficial blood collections was significantly lower in cases of Bionect application. No wound dehiscence was observed in cases, in which Bionect was used for wound care. One partial episiotomy dehiscence (10%) and one total cesarean section wound dehiscence were observed in standard wound treatment group. Excellent results in patients, treated with Bionect makes it a reasonable wound care option, especially in cases, when wound complications are expected.
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