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Therapeutic induction of abortion in the 1st and 2nd trimesters with intramuscular 15-methyl-prostaglandin F2 alpha

Göretzlehner, G.; Rudolf, K.; Frahm, R.

Zentralblatt für Gynakologie 99(22): 1356-1360

1977

ISSN/ISBN: 0044-4197
PMID: 602503
Document Number: 113676
Use of 15-methyl-prostaglandin F2 alpha to induce therapeutic abortion in 25 women is described. Repeated intramuscular (im) injections resulted in complete abortion in 2 patients, and incomplete abortion in 13 others. A 16th patient failed to abort. In 9 women in the 7-13th week of pregnancy, a single im injection induced cervical softening and dilatation before vacuum aspiration. Diarrhea and vomiting occurred in 19 patients. The authors recommend the use of anti-emetics and anti-diarrheals, or a lower initial dose, to control side effects. Evidence indicates 15-methyl-prostaglandin F2 alpha is a successful abortifacient.

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Rajan, R.; Subhadra, N.M.; Sarada, A.K.; Usha, D.L.; John, R. 1979: Evaluation of a lower dose schedule of intramuscular 15(S)-15-methyl prostaglandin F2 alpha for induction of early midtrimester abortion Journal of Obstetrics and Gynaecology of India 29(1): 38-43
Rajan, R.; Subhadra, N.M.; Sarada, A.K.; Usha, D.L.; John, R. 1979: Evaluation of a lower dose schedule of intramuscular 15(S)-15-methyl prostaglandin F2 alpha for induction of early midtrimester abortion Journal of Obstetrics and Gynaecology of India 29(1): 38-43
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