Central corneal thickness in the central retinal vein occlusion fellow eyes
Wanichwecharungruang, B.; Laophulsuk, V.; Sopitanont, S.; Vanichvaranont, S.; Harncharoen, K.
Journal of the Medical Association of Thailand 93(8): 943-949
2010
ISSN/ISBN: 0125-2208 PMID: 20718171 Document Number: 11354
To investigate the central corneal thickness (CCT) in the central retinal vein occlusion fellow eye (CRVO-fellow eye) patients. A cross-sectional study with 97 CRVO-fellow eye patients and 112 healthy subjects. Three measurements of CCT were obtained with ultrasonic pachymetry. Mean age of CRVO-fellow eye was higher than controls, 59.7 +/- 10.3 vs. 46.4 +/- 5.8 years, (p < 0.001). Males were more prevalent in CRVO-fellow eye than in the controls, 47.4% vs. 25%, (p = 0.001). In CRVO-fellow eye group, systemic diseases were more prevalent. Glaucoma and ocular hypertension were detected in 23 eyes (23.7%) of CRVO-fellow eye. Mean CCT of CRVO-fellow eye was thinner than controls, 529.2 +/- 30.3 vs. 543.3 +/- 31.8 on, (p = 0.001). Multiple linear regression models adjusted for age, sex, diabetes, hypertension, cup-to-disc ratio, IOP, and axial length revealed that mean CCT of CRVO-fellow eye was 16.9 microm thinner than controls. CRVO-fellow eye patients have thinner CCT than controls. The pathophysiology of this association is unclear It may be related to less lamina cribosa rigidity in the thin corneal eye. Lamina cribosa displacement may compress central retinal vein, leading to CR VO.
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