Interactions of salicylates and other nonsteroid anti-inflammatory agents
Royer, R.J.; Tamisier, J.N.; Netter, P.; Faure, G.; Gaucher, A.
La Semaine des Hopitaux Organe Fonde Par l'Association d'Enseignement Medical des Hopitaux de Paris 53(38): 2121-2124
1977
ISSN/ISBN: 0037-1777 PMID: 204021 Document Number: 113338
The salicylates are frequently associated in every day treatment with other non-steroid anti-inflammatory drugs, which justifies a study of their interactions. Animal pharmacodynamics, although interesting, is of little practical interest. Pharmacokinetic research seems to indicate that aspirin reduces the bio-availability of other non steroid anti-inflammatory drugs, which has not yet been confirmed clinically. It is still premature to conclude, but the already established facts suggest the continuation of such studies.