Myocardial function in patients with congenital pulmonary valve stenosis
Meshalkin, E.N.; Arkhipova, G.F.; Chasovskikh, G.G.; Odintsova, M.P.; Solov'ev, V.M.
Kardiologiia 17(7): 112-116
1977
ISSN/ISBN: 0022-9040 PMID: 200784 Document Number: 112562
The studies of metabolism and morphology of the myocardium, and of ECG parameters in 72 patients with valvular pulmonary stenosis conducted with biopsy and autopsy material has demonstrated that while the workload on the right ventricle grows and the severity of the pathological process increases, the oxidative capacity of the myocardium also increase, the indices of its energy supply decrease, the degree of myocytes hypertrophy grows, and the number of mitochondria and the coefficient of their energy efficacy decrease. A correlation was established between the degree of these changes and the severity of electrocardiographic signs of hypertrophy and disorders in the repolarization process in the right ventricle.