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Prevention of respiratory distress syndrome in pregnant diabetic women during labor

Nagy, G.; Kardos, Z.; Szeverényi, P.; Asztalos, M.

Zentralblatt für Gynakologie 99(25): 1541-1547

1977

ISSN/ISBN: 0044-4197
PMID: 610235
Document Number: 112524
In the period between 1973 and 1976, in order to prevent neonatal RDS, 24 insulin-dependent diabetic mothers were given Dexamethason before delivery. The treated group was compared with a control group comprising 26 women of the same gesational age, severity of diabetes and mode of delivery. Neonatal care was similar in both groups. In the group where steroid prophylaxis was applied, decrease of RDS morbidity and mortality was observed. The authors accentuate that Dexamethason given to the mother may have an unfavourable effect on carbohydrate metabolism. Therefore, it is recommended to perform 4-hour determinations of blood sugar, urinary sugar and acetone and accordingly, modification of therapy.

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