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Myosin and cardiac hypertrophy

Lêger, J.J.; Schwartz, K.; Swynghedauw, B.

Pathologie-Biologie 25(2): 75-80

1977

ISSN/ISBN: 0369-8114
PMID: 139588
Document Number: 111435
Myosin, which represents 1/4 of the weight of cardiac proteins, comprises virtually the entire composition of the dense filament of myofibrils. Its enzyme activity expresses the liberty necessary for contraction. The amino acid composition and sequence of cardiac myosin differs from that of skeletal muscle myosin, and differs from animal to animal. The sequence of a single peptide isolated from the heavy myosin chains is characteristic for each animal species. Incubation of rabbit and dog myosin at an alkaline pH for 10 min causes a large decrease in enzyme activity, but rat cardiac myosin is unaffected by this treatment. There is a similar difference between these animal species in response to N-ethylmaleimide, which reacts with sulfur linkages. K-dependent cardiac myosin activity is the same for different animals, but values differ for Ca-dependent activity in man, dog, guinea pig, rat and mouse.

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Schwartz, K.; Carrier, L.; Chassagne, C.; Wisnewsky, C.; Boheler, K.R. 1992: Regulation of myosin heavy chain and actin isogenes during cardiac growth and hypertrophy Symposia of the Society for Experimental Biology 46: 265-272
Sugi, H. 2011: Electron microscopic visualization of the myosin head dynamics to ATP in myosin filaments using the gas environmental chamber. Ii novel approach for movement of myosin head with ATP hydrolysis Nihon Seirigaku Zasshi. Journal of the Physiological Society of Japan 73(6): 150-162
Pummerer, C.L.; Grässl, G.; Sailer, M.; Bachmaier, K.W.; Penninger, J.M.; Neu, N. 1996: Cardiac myosin-induced myocarditis: target recognition by autoreactive T cells requires prior activation of cardiac interstitial cells Laboratory Investigation; A Journal of Technical Methods and Pathology 74(5): 845-852
Robberecht, P.; Waelbroeck, M.; Claeys, M.; Huu, A.N.; Chatelain, P.; Christophe, J. 1982: Rat cardiac muscarinic receptors. II. Influence of thyroid status and cardiac hypertrophy Molecular Pharmacology 21(3): 589-593
Pagano, V.T.; Inchiosa, M.A. 1979: Characterization of the decreased ATPase activity of rat cardiac actomyosin in isoproterenol-induced cardiac hypertrophy Research Communications in Chemical Pathology and Pharmacology 23(1): 37-47
Smirnov, I.E.; Fatkhullin, I.A.; Markov, K.M. 1990: Production of cardiac prostanoids and the fatty acid composition of cardiac phospholipids in various types of myocardial hypertrophy Patologicheskaia Fiziologiia i Eksperimental'naia Terapiia 6: 10-13
Pelouch, V.; Deyl, Z.; Poupa, O. 1970: Myosin aggregation in cardiac necroses induced by isoproterenol in rats Physiologia Bohemoslovaca 19(1): 9-13
Syrový, I.; Gutmann, E. 1975: Myosin from fast and slow skeletal and cardiac muscles of mammals of different size Physiologia Bohemoslovaca 24(4): 325-334
Syrový, I. 1984: Effects of temperature on rat and mouse cardiac myosin ATPase activity during development Physiologia Bohemoslovaca 33(4): 376-380
Goswami, S.K.; Zarraga, A.M.; Martin, M.E.; Morgenstern, D.; Siddiqui, M.A. 1992: Fos-mediated repression of cardiac myosin light chain-2 gene transcription Cellular and Molecular Biology 38(1): 49-58
Kuleva, N.V.; Karandashov, E.A.; Panteleeva, N.S. 1970: The effect of trinitrophenylation of myosin on the oxygen isotope exchange reaction in a myosin--ATP--H20-18 system Biokhimiia 35(1): 42-47
Walzthöny, D.; Eppenberger, H.M.; Ueno, H.; Harrington, W.F.; Wallimann, T. 1986: Melting of myosin rod as revealed by electron microscopy. II. Effects of temperature and pH on length and stability of myosin rod and its fragments European Journal of Cell Biology 41(1): 38-43
Printsev, M.D.; Frolova, N.I.; Ivanteeva, E.P.; Korovkin, B.F. 1984: Ca2+-dependent phosphorylation and ATPase activity of cardiac muscle myosin in experimental myocardial infarction Voprosy Meditsinskoi Khimii 30(6): 68-71
Dubonos, V.M.; Danylova, V.M.; Haluskho, V.O.; Trehubov, V.S.; Bohach, P.H. 1977: Comparative electrophoretic studies of native myosin and myosin treated with sodium dodecyl sulfate from smooth and skeletal muscles Ukrains'kyi Biokhimichnyi Zhurnal 49(5): 109-114
Metzger, J.M. 1996: pH dependence of myosin binding-induced activation of the thin filament in cardiac myocytes and skeletal fibers American Journal of Physiology 270(3 Pt 2): H1008-H1014
Pummerer, C.; Berger, P.; Frühwirth, M.; Ofner, C.; Neu, N. 1991: Cellular infiltrate, major histocompatibility antigen expression and immunopathogenic mechanisms in cardiac myosin-induced myocarditis Laboratory Investigation; a Journal of Technical Methods and Pathology 65(5): 538-547
Li, M.; Cheng, K.; Wang, Q.-B.; Zhu, W.-Q.; Qin, S.-M.; Cui, J.; Shu, X.-H.; Chen, R.-Z.; Ge, J.-B.; Chen, H.-Z. 2009: Link between cardiac myosin binding protein-C gene mutation of Pro1208fs and Gly507 Arg and hypertrophic cardiomyopathy in Chinese patients Zhonghua Xin Xue Guan Bing Za Zhi 37(9): 790-793
Hayashida, W.; Kihara, Y.; Sasayama, S. 2000: Cardiac hypertrophy associated with hypertension: its management Nihon Rinsho. Japanese Journal of Clinical Medicine 58(Suppl 2): 305-308
Burchell, H.B. 1974: Clinical recognition of cardiac hypertrophy Circulation Research 35(2): Suppl Ii: 116-21
Yorikane, R.; Sakai, S.; Miyauchi, T.; Sakurai, T.; Goto, K. 1994: Possible involvement of endothelin-1 in cardiac hypertrophy Arzneimittel-Forschung 44(3a): 412-415