Suppressive effect of copper on ethylation of rat liver DNA with ethionine in vivo
Yamane, Y.; Sakai, K.; Shibata, M.; Chiba, K.
Gan 68(5): 713
1977
ISSN/ISBN: 0016-450X PMID: 590689 Document Number: 111163
Effect of Cu on ethylation of rat liver DNA with the carcinogen ethionine in vivo was examined. Ethylation with ethionine was markedly suppressed by the administration of dietary Cu and Cu accumulated in rat liver DNA.
Document emailed within 1 workday
Related Documents
Farber, J.L.; Shinozuka, H.; Serroni, A.; Farmar, R. 1974: Reversal of the ethionine-induced inhibition of rat liver ribonucleic acid polymerases in vivo by adenine Laboratory Investigation; a Journal of Technical Methods and Pathology 31(5): 465-472Garg, B.D.; Szabo, S.; Kovacs, K.; Tuchweber, B. 1974: Effect of cycloheximide and dl-ethionine on the liver ultrastructure of hypophysectomized rats Zeitschrift für Mikroskopisch-Anatomische Forschung 88(5): 948-956
McQuaid, A.; Lamand, M.; Mason, J. 1992: The interactions of penicillamine with copper in vivo and the effect on hepatic metallothionein levels and copper/zinc distribution: the implications for Wilson's disease and arthritis therapy Journal of Laboratory and Clinical Medicine 119(6): 744-750
Roitenburd Belacortu, V. 1987: Effect of ethionine on the liver of rats under conditions of different amounts of protein in the diet Revista de Investigacion Clinica; Organo del Hospital de Enfermedades de la Nutricion 39(1): 19-27
Kaemmerer, K.; Kietzmann, M. 1983: Effect of copper sulfate and copper chelates on the liver protein synthesis Deutsche Tierärztliche Wochenschrift 90(1): 1-4
Shibuya, H. 1987: Experimental study on rat hepatic injury by copper--effect of copper overload on the cholestatic liver induced by bile duct ligation Hokkaido Journal of Medical Science 62(3): 434-441
Hultgren, B.D.; Stevens, J.B.; Hardy, R.M. 1986: Inherited, chronic, progressive hepatic degeneration in Bedlington terriers with increased liver copper concentrations: clinical and pathologic observations and comparison with other copper-associated liver diseases American Journal of Veterinary Research 47(2): 365-377
Wainfan, E.; Moller, M.L.; Maschio, F.A.; Balis, M.E. 1975: Ethionine-induced changes in rat liver transfer RNA methylation Cancer Research 35(10): 2830-2835
Saito, S. 1996: The effect of copper on zinc in liver and in metallothionein Research Communications in Molecular Pathology and Pharmacology 94(3): 259-264
Kim, J.W.; Kim, J.H.; Shin, J.E.; Kil, D.Y. 2016: Relative bioavailability of copper in tribasic copper chloride to copper in copper sulfate for laying hens based on egg yolk and feather copper concentrations Poultry Science 95(7): 1591-1597
Torlińska, T.; Grzymisławski, M.; Paluszak, J.; Sosnowski, P.; Torliński, L.; Koźlik, J. 1987: Triiodothyronine effect on some parameters of carbohydrate metabolism in rat blood and liver. I. in vivo effect of triiodothyronine on liver glycogen content, blood metabolites and serum glycogenolytic activity Acta Physiologica Polonica 38(4): 353-360
Wang, B.S.; Heacock, E.H.; Collins, K.H.; Hutchinson, I.F.; Tilney, N.L.; Mannick, J.A. 1981: Suppressive effects of cyclosporin a on the induction of alloreactivity in vitro and in vivo Journal of Immunology 127(1): 89-93
Mahmoud, O.H.; Ford, E.J. 1982: Changes in the liver copper content of Welsh mountain sheep after the injection of organic compounds of copper Veterinary Record 111(23): 534-535
Bloxam, D.L.; Fisher, M.M. 1974: Effects of ethionine on amino acid concentrations in liver and blood of male and female rats Laboratory Investigation; a Journal of Technical Methods and Pathology 31(6): 705-711
Irons, R.D.; Schenk, E.A.; Lee, J.C. 1977: Cytochemical methods for copper. Semiquantitative screening procedure for identification of abnormal copper levels in liver Archives of Pathology and Laboratory Medicine 101(6): 298-301
Bryant, H.U.; Roudebush, R.E. 1990: Suppressive effects of morphine pellet implants on in vivo parameters of immune function Journal of Pharmacology and Experimental Therapeutics 255(2): 410-414
Sidransky, H.; Verney, E. 1970: Influence of orotic acid on liver tumorigenesis in rats ingesting ethionine, N-2-fluorenylacetamide, and 3'-methyl-dimethylaminoazobenzene Journal of the National Cancer Institute 44(5): 1201-1215
Pan'kova, N.V.; Karamyshev, A.L.; Shliapnikov, M.G.; Presich, A.N.; Ksenzenko, V.N. 1998: Amber-suppressive tRNA from bacteriophage T5: construction of genes and determination of the effectiveness of suppression in vivo Molekuliarnaia Biologiia 32(6): 1004-1012
Bíres, J. 1989: Interactive relations between copper, iron, zinc, arsenic, cadmium and lead in the liver in sheep after experimental poisoning with copper oxide Veterinarni Medicina 34(11): 665-674
Brada, Z.; Altman, N.H.; Bulba, S. 1975: The effect of cupric acetate on ethionine metabolism Cancer Research 35(11 Part 1): 3172-3180