Non-steroid anti-inflammatory agents. Stereoisomers of 2- (-4-biphenylyl) -3-oxybutyric acid
Guarnieri, A.; Scapini, G.; Burnelli, S.; Andreani, A.
Il Farmaco; Edizione Scientifica 32(5): 324-332
1977
ISSN/ISBN: 0430-0920 PMID: 862887 Document Number: 110951
The synthesis, diastereoisomeric separation, attribution to erythro and threo series, and resolution of the enantiomers of 2-(4-biphenylyl)-3-oxybutyric acid are described. The four isomers were tested for anti-inflammatory activity: the preliminary results are interesting, particular those for the (--) erythro enantiomer.
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