Coexisting tardive dyskinesia and parkinsonism: a case report
De Fraites, E.G.; Davis, K.L.; Berger, P.A.
Biological Psychiatry 12(2): 267-272
1977
ISSN/ISBN: 0006-3223 PMID: 857938 Document Number: 110655
A case report is presented of a patient with remitting tardive dyskinesia coexistent with neuroleptic-induced parkinsonism. The patient received benztropine and physostigmine challenges on successive days and the effects on both syndromes are described. The clinical course of both diseases is discussed in terms of a balance hypothesis between dopaminergic and cholinergic neurotransmission.