On glutamate dehydrogenase interaction with sex hormones
Titova, G.V.; Kliueva, N.N.
Biokhimiia 42(4): 635-638
1977
ISSN/ISBN: 0320-9725 PMID: 558001 Document Number: 110153
The effect of sex hormones on the activity of glutamate dehydrogenase from beef liver was studied in vitro. The inhibitory effect of the hormones was relieved both when the guanidine groups of the enzyme were blocked and when L-arginine was added to the reaction mixture. The data obtained suggest that the guanidine groups of the arginine residues of the enzyme are involved in the realization of the inhibitory effect of the hormones.