Analysis of several clinical, morphologic and biochemical responses to vaccination from the point of view of normal and pathologic conditions
Vorob'ev, A.A.; Prigoda, A.S.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 12: 10-15
1976
ISSN/ISBN: 0372-9311 PMID: 799449 Document Number: 109900
Induction of specific immunity under the effect of the antigens is unthinkable without the participation in this process of the reticuloendothelial system, other organs and systems of the vaccinated organism with the inversion of the total immunological reactivity of the vaccinated individual. Of great significance for the success of a definite vaccination is correlation of the functions of specific and nonspecific immunity. At the same time, counting many changes in the organs and systems of the person vaccinated as natural and necessary, one should also consider possibilities of a number of unfavourable side-reactions following vaccination as a result of some causes. The survey analyzes the principal immunobiological indices of the vaccinated organism and also assesses their established or probable role in the immunity system.