Top Abstract Purchase Related
Home
>
Node
>
Subnode

Relationship between beta-lactamase activity of clinical strains of Pseudomonas pyocyanea and their resistance to penicillins

Gromova, G.N.

Antibiotiki 21(4): 344-349

1976

ISSN/ISBN: 0003-5637
PMID: 818952
Document Number: 109194
The study of 50 clinical strains of Ps. aeruginosa revealed their high resistance to benzylpenicillin, ampicillin, oxacillin, streptomycin and kanamycin with a tendency to polyresistance. The same strains were highly sensitive to gentamycin and polymyxin. The strains produced constitutive beta-lactamase in small amounts. The enzyme synthesis in Ps. aeruginosa was induced by benzylpenicillin. Still high concentrations of it were required for the induction. The maximum induction of beta-lactamase synthesis was observed by the 6th hour of the inductor addition. The maximum induction level was observed 4 hours after addition of benzylpenicillin. The level of induction of beta-lactamase synthesis in the strains ranged within 5-93. A significant part of the enzyme was liberated from the cells during induction. Interaction between the induction level of beta-lactamase synthesis and resistance of Ps. aeruginosa to penicillins was found.

Document emailed within 1 workday
Secure & encrypted payments

Mereuţă, A.I.; Tuchiluş, C.; Bădescu, A.C.; Iancu, L.ţa.S. 2011: Metallo-beta-lactamase-mediated resistance among carbapenem-resistant Pseudomonas aeruginosa clinical isolates Revista Medico-Chirurgicala a Societatii de Medici Si Naturalisti Din Iasi 115(4): 1208-1213
Jacobs, M.R.; Aronoff, S.C.; Johenning, S.; Shlaes, D.M.; Yamabe, S. 1986: Comparative activities of the beta-lactamase inhibitors YTR 830, clavulanate, and sulbactam combined with ampicillin and broad-spectrum penicillins against defined beta-lactamase-producing aerobic gram-negative bacilli Antimicrobial Agents and Chemotherapy 29(6): 980-985
Michel-Briand, Y.; Nicolas, T.; Godard, C.; Plesiat, P. 1992: Beta-Lactamase Id of ceftazidime-resistant Pseudomonas aeruginosa strains Microbiologica 15(1): 65-69
Oguike, J.U.; Gugnani, H.C.; Osuagwu, C. 1991: A note on penicillin resistance and beta-lactamase production in strains of Staphylococcus aureus recovered from different clinical materials in Nsukka, Nigeria Journal of Communicable Diseases 23(3): 200-201
Shahcheraghi, F.; Nikbin, V.S.; Feizabadi, M.M. 2010: Identification and genetic characterization of metallo-beta-lactamase-producing strains of Pseudomonas aeruginosa in Tehran, Iran New Microbiologica 33(3): 243-248
Atilla, A.; Eroğlu, C.; Esen, S.; Sünbül, M.; Leblebicioğlu, H. 2012: Investigation of the frequency of PER-1 type beta-lactamase and antimicrobial resistance rates in nosocomial isolates of Pseudomonas aeruginosa Mikrobiyoloji Bulteni 46(1): 1-8
Baykal, A.; Cöplü, N.; Simşek, H.üs.; Esen, B.; Gür, D. 2012: The presence of extended spectrum beta-lactamase, KPC-type carbapenemase and plasmid-mediated AmpC beta-lactamase in E.coli and K.pneumoniae strains isolated from blood cultures Mikrobiyoloji Bulteni 46(2): 159-169
Zhang, W.-l.; Liu, J.; Zhang, J.; Su, G.-l. 2011: Analysis of antibiotic resistance and genotypes on extended spectrum β-lactamase and AmpC β-lactamase producing strains isolated from Uygur and Han newborns Zhonghua Yu Fang Yi Xue Za Zhi 45(3): 217-224
Neu, H.C.; Chin, N.X. 1985: A perspective on the present contribution of beta-lactamases to bacterial resistance with particular reference to induction of beta-lactamase and its clinical significance Chemioterapia: International Journal of the Mediterranean Society of ChemoTherapy 4(1): 63-70
Moreva, T.V.; Anisimova, L.A.; Erova, T.E.; Boronin, A.M. 1992: Amikacin resistance of clinical strains of Enterobacteriaceae and Pseudomonas Antibiotiki i Khimioterapiia 37(4): 25-28
Shiono, A.; Kurihara, J.; Hayashi, M.; Suzuki, T.; Imai, K.; Yamanaka, H.; Takezawa, Y.; Kiren, H.; Okabe, K.; Tomaru, Y. 1993: Clinical evaluation of Augpenin (clavulanic acid-ticarcillin) in urinary tract infections: especially against beta-lactamase producing strains Hinyokika Kiyo. Acta Urologica Japonica 39(8): 777-782
Rosenthal, E. 1984: In-vitro activity of new beta-lactam antibiotics. Testing resistant enterobacteria and pseudomonas aeruginosa strains Fortschritte der Medizin 102(41): 1051-1052
Comanducci, A.; Piccolomini, R.; Oliva, B. 1976: Study of the action of combinations of beta-lactam antibiotics on the beta-lactamase produced by strains of Enterobacteriaceae Bollettino della Societa Italiana di Biologia Sperimentale 52(18): 1433-1439
Alós, J.I.; Oteo, J. 1999: Resistance to the combination of beta-lactams and beta-lactamase inhibitors Revista Espanola de Quimioterapia: Publicacion Oficial de la Sociedad Espanola de Quimioterapia 12(3): 205-210
Soina, K.K.; Razykov, A.A.; Mustafina, A.K. 1989: Beta-Lactamase-producing strains of the gonococcus Vestnik Dermatologii i Venerologii 6: 57-58
Bobrowski, M.M. 1974: Bacterial beta-lactamases and their significance in resistance to penicillins and cephalosporins Postepy Higieny i Medycyny Doswiadczalnej 28(4): 587-603
Masiukova, S.A.; Shakhabiddinov, T.T.; Shadyev, K.K.; Dmitriev, G.A.; Delektorskiĭ, V.V. 1990: Chronic pyoderma caused by beta-lactamase-producing strains of Staphylococcus Vestnik Dermatologii i Venerologii 5: 48-53
Sienkiewicz, M.; Wasiela, M.łg.; Głowacka, A. 2012: The antibacterial activity of oregano essential oil (Origanum heracleoticum L.) against clinical strains of Escherichia coli and Pseudomonas aeruginosa Medycyna Doswiadczalna i Mikrobiologia 64(4): 297-307
Stewardson-Krieger, P.; Naidu, S. 1981: Simultaneous recovery of beta-lactamase-negative and beta-lactamase-positive Haemophilus influenzae type b from cerebrospinal fluid of a neonate Pediatrics 68(2): 253-254
Bayraktar, B.; Toksoy, B.; Bulut, E. 2010: Detection of bla(CTX-M) beta-lactamase genes in extended-spectrum beta-lactamase producing gram-negative bacteria Mikrobiyoloji Bulteni 44(2): 187-196