Deletion - translocation del (12) (p11) leads to (t10;12) (p13;pII)
Nielsen, J.; Rasmussen, K.; Niebuhr, E.
Annales de Genetique 19(1): 53-55
1976
ISSN/ISBN: 0003-3995 PMID: 1084123 Document Number: 108392
Renewed examinatinon with improved banding techniques of a boy previously reported to have the karyotype 46, XY,del(12)(p11) revealed a translocation 46, XY,t(10;12)(p13;p11), and reexamination of a boy previously reported to have the karyotype 46,XY/46,XY,del(5)(p13) showed the same mosaicism, but with a significantly lower frequency of cells with del(5)(p13), 8% compared with 23% at the time of birth. The decrease of the frequency of cells with chromosome abnormality in mixoploids during the first years of life as found in the present case as well as in prevously reported cases is discussed.