Bioenergetics in clinical medicine. VI. adjunctive treatment of periodontal disease with coenzyme Q10
Wilkinson, E.G.; Arnold, R.M.; Folkers, K.
Research Communications in Chemical Pathology and Pharmacology 14(4): 715-719
1976
ISSN/ISBN: 0034-5164 PMID: 785563 Document Number: 108149
Eighteen patients with periodontal disease and measurable pockets were treated on a double-blind basis with coenzyme Q10 and a maching placebo. The treatment was significant (p less than 0.01). Before decoding, all 8 patients receiving coenzyme Q10 and 7/10 patients receiving placebo were correctly assigned. Of the remaining 3 placebo patients, the status of one was borderline and could have been assigned to either group, and two improved due to better hygiene. Crevicular fluid flow as a measure of inflammation was newly monitored. Pocket-depth, periodontal health, calculus and plaque scores provided the most valuable data for evaluation.