Etiology of postobstructive diuresis: ouabain-sensitive adenosine triphosphatase deficit and elevated solute excretion in the postobstructed dog kidney

Williams, R.D.; Fanestil, D.D.; Blackard, C.E.

Investigative Urology 14(2): 148-152

1976


ISSN/ISBN: 0021-0005
PMID: 134977
Document Number: 106765
A selective deficit in ouabain-sensitive adenosine triphosphatase has been shown in unilaterally obstructed dog kidneys; the deficit correlates inversely with Na+ and K+ excretion following relief of obstruction. It is postulated that the enzymatic defect may play a role in the etiology of postobstructive diuresis.

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