Hemoglobins of the opossum (Didelphis marsupialis) . II. Polymorphism; electrophoretic and chromatographic observations

Bethlenfalvay, N.C.; Brown, G.L.; Waterman, M.R.

Laboratory Animal Science 26(6 Part 1): 908-912

1976


ISSN/ISBN: 0023-6764
PMID: 1018476
Document Number: 106453
Eighty-five adult opossums (Didelphis marsupialis) were examined for variation of hemaglobin by means of electrophoresis and column chromatography. A single hemoglobin was found in 83 animals while two hemoglobins were observed in two animals. The results of the chromatography studies suggested that the polymorphism was due to primary sequence differences in the alpha chain. Attempts to confirm this result by hybridization with human or canine hemoglobins were unsuccessful. The polymorphism was found not to be due to size differences and further investigation into its genetic basis was suggested.

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