Scabies masquerading as Letterer-Siwe's disease
Aterman, K.; Krause, V.W.; Ross, J.B.
Canadian Medical Association Journal 115(5): 443-444
1976
ISSN/ISBN: 0008-4409 PMID: 953920 Document Number: 105692
Letterer-Siwe's disease was diagnosed from clinical appearance and initial assessment of a skin biopsy in a child with a 2-month history of skin rash. Fine erythematous papules were scattered on the trunk. The biopsy showed epidermal thickening and an inflammatory infiltrate chiefly in the upper layers of the dermis; deeper in the dermis the infiltrate was perivascular and periappendicular, histiocytes predominating in some areas and lymphocytes in others. A diagnosis of scabies was made after burrows were demonstrated on palms and soles and the mite of scabies was isolated from them.