Testicular secretions of androgens after prolonged physical effort in man

De Lignières, B.; Plas, J.N.; Commandre, F.; Morville, R.; Viani, J.L.; Plas, F.

La Nouvelle Presse Medicale 5(32): 2060-2064

1976


ISSN/ISBN: 0301-1518
PMID: 980728
Document Number: 105395
Variations in plasma testosterone, dihydrotestosterone. delta 4 androstenedione, LH, FSH and cortisol were measured before and after 6 succesive effort tests in 11 male subjects. Testicular secretion and the extra-hepatic consumption of androgens are increased by the haemodynamic conditions of effort but plasma levels of testosterone and dihydrotestosterone fall with repeated effort, indicating a progressive imbalance between production and consumption. These variations suggest that the testis, rather than glucocorticoid function of the adrenal, might play a major limiting role, psychological and metabolic, in tolerance of prolonged effort.

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