A case report of tumor-induced osteomalacia: eight year followed-up
Ratanasuwan, T.; Chetsurakarn, S.; Ongphiphadhanakul, B.; Damrongkitchaiporn, S.
Journal of the Medical Association of Thailand 91(12): 1900-1902
2008
ISSN/ISBN: 0125-2208 PMID: 19133527 Document Number: 10460
Tumor-induced osteomalacia (TIO) is a rare but potentially curable disease. It is caused by excessive renal clearance ofphosphate induced by a substance secreted from the tumor Here, the authors report a Thai patient who presented with multiple pathologic fractures, low serum phosphorus, and low tubular maximum reabsorption of phosphorus/glomerular filtration rate (TmPO4/GFR). The clinical, biochemical and bone abnormalities improved 6 months after the surgery. Two years follow-up showed no recurrence of the disease. Physicians should be aware of this condition when encountering with adult onset osteomalacia.
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