Rosette tests in lymphoproliferative diseases
Michlmayr, G.; Pathouli, C.; Falkensammer, M.; Huber, C.; Huber, H.; Braunsteiner, H.
Schweizerische Medizinische Wochenschrift 106(23): 794-799
1976
ISSN/ISBN: 0036-7672 PMID: 792996 Document Number: 104204
The percentage and absolute count of B- and T-lymphocytes in the peripheral blood of 170 patients with various lymphoproliferative diseases was determined. T-lymphocytes were assessed by their capacity to form rosettes with unsensitized neuraminidase treated sheep red blood cells, and B-lymphocytes by their capacity to bind immune-complement complexes. The results in CLL, in non-Hodgkin lymphoma and in Hodgkin's disease are discussed with respect to the immunopathology of these diseases.