Optimization in freeze-drying
Rowe, T.W.
Developments in Biological Standardization 36: 79-97
1976
ISSN/ISBN: 0301-5149 PMID: 1030439 Document Number: 103876
The author assumes that success in freeze-drying must be judged in economic terms. Following a summary of the reasons given for adopting freeze-drying, and an historical outline to explain the changing emphasis in the performance requirements of equipment, desirable features in design and operation are reviewed as the basis for a charter for plant manufacturers and an aid to comparison between different types of plant. Ways of appraising value for money are examined and a novel method is proposed for maximizing throughput by optimising the conditions in the freeze-dryer.