12 years of medical treatment of Cushing's disease. Long-term use of Op, DDD in 46 cases
Bricaire, H.; Luton, J.P.
La Nouvelle Presse Medicale 5(6): 325-329
1976
ISSN/ISBN: 0301-1518 PMID: 1264700 Document Number: 102812
The authors report the results of the medical treatment in 46 cases of Cushing's disease. Long-term Op,DDD therapy apparently results in a drug-induced total adrenal suppression in 28 cases. In 12 cases it reduces the adrenal secretion down to the normal level. In only 6 cases of this series was the treatment unsuccessful. Accordingly the authors think that long-term medical treatment with Op,DDD deserves to be considered as a major total tool within the therapy of Cushing's disease. However regular and precise monitoring under therapy is necessary. The schema of the method used is described.