Clonazepam in the treatment of choreiform activity
Peiris, J.B.; Boralessa, H.; Lionel, N.D.
Medical Journal of Australia 1(8): 225-227
1976
ISSN/ISBN: 0025-729X PMID: 131236 Document Number: 102715
In a limited study, clonazepam, a new benzodiazepine derivative, has been found to be effective in suppressing choreiform movements in three patients with Huntington's chorea, three patients with non-familial chorea, and in one patient with senile chorea. In two patients with chorea of doubtful aetiology the response was not very satisfactory. A simple method was used to assess objectively the effect on choreiform movements. The effective dose varied from 3-5 to 5-5 mg a day. The drug was well tolerated by most of the patients.