Thrombolysis for prosthetic valve malfunction: case report and review
Chaiworramukkun, J.; Chandanamattha, P.; Boonbaichaiyapruck, S.
Journal of the Medical Association of Thailand 86 Suppl. 1: S110-S115
2003
ISSN/ISBN: 0125-2208 PMID: 12866777 Document Number: 10226
A 40 year old female with severe mitral valve stenosis, underwent mitral valve replacement by single disc valve 4 years ago. She presented at this admission with a new onset of congestive heart failure. The prothrombin time was inadequate with international normalized ratio (INR) 1.43. Transthoracic echocardiography revealed high pressure gradient across the mitral valve. Fluoroscopy demonstrated restrictive opening of single disc motion. Intravenous thrombolysis was given for presumptive diagnosis of prosthetic valve thrombosis. The patient gradually improved and did not have to undergo surgical correction.